Share 'Business opportunities for an immigrant in US'

Hi, First of all , I would like to thank to the founder of this site ... My question is reagarding the legal issue ... i am about to graduate with a PhD and want to start my own web startup, I have my website ready ... the problem is,I neither have a citizenship nor I am a permanent resident (green card) ... I am on F1 visa which is also about to expire ... in this case can I still start my c...